PDE5 INHIBITORS

Not only sildenafil citrate (Viagra) but all of the other currently available phosphodiesterase 5 inhibitors used for erectile dysfunction may increase the risk of central serous chorioretinopathy (CSC). Two case studies of patients who developed taking PDE5 inhibitors (vardenafil and tadalafil) for erectile dysfunction showed that the condition resolved once they discontinued use of the agents but reappeared when they resumed using it and once again resolved when they stopped using it the second time. The authors of the study note that there have been previous reports of CSC in patients taking sildenafil citrate. Previous studies have also indicated a link between the use of PDE5 inhibitors and other ocular side effects, including lid oedema, hyposphagma, photophobia, mydriasis, dyschromatopsia, and nonarteritic anterior ischemic optic neuropathy. The evidence suggests CSC may be another rare PDE5 inhibitor class-specific side effect, the study’s authors said
(Aliferis et al, Ophthalmogica 2012; 227:85-89)
Latest Articles
Beyond the Numbers
Empowering patient participation fosters continuous innovation in cataract surgery.
Thinking Beyond the Surgery Room
Practice management workshop focuses on financial operations and AI business applications.
Aid Cuts Threaten Global Eye Care Progress
USAID closure leads retreat in development assistance.
Supplement: ESCRS Clinical Trends Series: Presbyopia
Nutrition and the Eye: A Recipe for Success
A look at the evidence for tasty ways of lowering risks and improving ocular health.
New Award to Encourage Research into Sustainable Practices
Sharing a Vision for the Future
ESCRS leaders update Trieste conference on ESCRS initiatives.
Extending Depth of Satisfaction
The ESCRS Eye Journal Club discuss a new study reviewing the causes and management of dissatisfaction after implantation of an EDOF IOL.
Conventional Versus Laser-Assisted Cataract Surgery
Evidence favours conventional technique in most cases.
AI Scribing and Telephone Management
Automating note-taking and call centres could boost practice efficiency.