CORRELATION BETWEEN SUN SCALE GRADES AND ANTERIOR CHAMBER CELL COUNTS MEASURED BY CORNEAL-OCT IN PAEDIATRIC UVEITIS PATIENTS: A DETAILED STUDY
Published 2025 - 29th ESCRS Winter Meeting
Reference: PP02.10 | Type: Presented Poster & Poster | DOI: 10.82333/ht52-t868
Authors: Ali Ibrahim* 1 , Anas Injarie 2
1Norfolk & Norwich University Hospital,Norwich,United Kingdom, 2Ophthalmology,Norfolk & Norwich University Hospital,Norwich,United Kingdom
Purpose
This study aimed to evaluate the correlation between the Standardisation of Uveitis Nomenclature (SUN) scale and anterior chamber cell counts measured by Corneal-optical coherence tomography (Corneal-OCT) in paediatric uveitis patients. We hypothesised that focusing on the central 7 frames of Corneal-OCT scans would enhance the repeatability and accuracy of inflammation assessments due to the anatomical significance of these frames, and because this approach simplifies the imaging process, which is particularly beneficial when scanning children.
Setting
This study was conducted in a hospital setting involving paediatric uveitis patients attending ophthalmology clinics.
Methods
A total of 93 clinical visits were analysed in paediatric patients aged 16 or under who underwent regular uveitis screenings over a 20-month period. All patients had Corneal-OCT imaging performed on the same day as their clinical review, with only OCT scans containing at least 9 frames included in the analysis. The distribution of SUN Scale grades was as follows: 46 episodes at grade 0, 19 at grade 0.5, 13 at grade 1, 11 at grade 2, and 7 at grade 3. Spearman’s rank correlation was used to assess the relationship between SUN Scale grades and mean cell counts, with statistical analyses conducted using R software.
Results
The analysis revealed a strong positive correlation between SUN Scale grades and mean cell counts (ρ = 0.920, p < 2.2e-16). Focusing on the central 7 frames of the Corneal-OCT scans improved repeatability and mitigated issues related to patient movement and inadequate scans.
Conclusion
The findings confirm that using Corneal-OCT, particularly focusing on the central 7 frames, provides a reliable and repeatable method for assessing anterior chamber inflammation in paediatric uveitis patients. These results support the routine integration of Corneal-OCT into clinical practice, offering enhanced accuracy and consistency in monitoring uveitis in children.