ESCRS - PO289 - THERAPEUTIC CUSTOMIZED SURFACE EXCIMER LASER ABLATION TO MANAGE SEVERE CONTACT LENS-RELATED (CLR) INFECTIOUS KERATITIS-ASSOCIATED CORNEAL SCARRING.

THERAPEUTIC CUSTOMIZED SURFACE EXCIMER LASER ABLATION TO MANAGE SEVERE CONTACT LENS-RELATED (CLR) INFECTIOUS KERATITIS-ASSOCIATED CORNEAL SCARRING.

Published 2025 - 29th ESCRS Winter Meeting

Reference: PO289 | Type: Free Paper | DOI: 10.82333/ywbz-ck54

Authors: Despoina Karadimou* 1 , Anastasios John Kanellopoulos 2 , Alexandros Kanellopoulos 1

1Ophthalmology,Laservision Ambulatory Eye Surgery Unit,Athens,Greece, 2Ophthalmology,Laservision Ambulatory Eye Surgery Unit,Athens,Greece;Ophthalmology,NYU Med School,New York,United States

Purpose

To evaluate the safety and efficacy of therapeutic custom surface excimer ablations designed to address corneal scars from infections  related to contact lens use.

Setting

The Laservision Clinical and Research Institute, Athens, Greece

Methods

7 cases of CLR corneal scarring, due to infection, were treated with a surface excimer laser transepithelial ablation in order to remove the scar tissue and normalize the refractive power of the cornea, using a topography-guided customization platform (Alcon/Wavelight, Erlagen, Germany)

Results

At 3 months postoperatively, significantly improved corneal transparency was noted in all cases, CDVA improved from a mean of 20/50 to 20/30. UDVA changed from 20/200 to 20/40. A keratoplasty procedure was avoided in all cases.

Conclusion

Customized excimer laser ablations can offer significant therapeutic improvement in challenging cases with CLR corneal scars due to previous infection vision. They may be considered as an alternative to lamellar and or penetrating keratoplasty.