THE EFFECT OF EARLY POSTTRABECULECTOMY BLEB LEAKAGE ON SURGICAL OUTCOME: A PROSPECTIVE COHORT STUDY
Published 2025 - 29th ESCRS Winter Meeting
Reference: PO282 | Type: Free Paper | DOI: 10.82333/3raz-ke29
Authors: Nader Nassiri* 1 , Kourosh Sheibani 2 , Sara Kavousnezhad 3 , Maryam Yadgari 1
1Ophthalmology,Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences ,Tehran,Iran, Islamic Republic Of, 2Basir Eye Health Research Center,Tehran,Iran, Islamic Republic Of, 3Vanak Eye Surgery Center,Tehran,Iran, Islamic Republic Of
Purpose
To evaluate the effect of early post trabeculectomy bleb leakage on trabeculectomy surgery outcomes and success rate.
Setting
Torfeh and Imam Hossein Medical Centers, Tehran, Iran
Methods
The present prospective cohort study was conducted on 203 eyes of 203 patients who underwent trabeculectomy between 2016 and 2021. Patients were divided into two groups: those with early bleb leakage (within the 1st month of surgery) and those without bleb leakage. The success rate of surgery was compared 12, 18, and 24 months after surgery in the two groups. The average intraocular pressure (IOP) and the need for medications in patients 1, 3, 6, 9, 12, 18, and 24 months after the trabeculectomy were also compared.
Results
Bleb leakage was detected in 33 eyes during the 1st month after a trabeculectomy (16.3%). The mean decrease in IOP in the group with leakage was significantly lower than in patients without leakage at 1, 6, 9, 12, 18, and 24 months after surgery (P <0.05). The need for antiglaucoma medication was significantly higher among patients with bleb leakage at 3 months (P = 0.04) and 9 months (P = 0.047) after surgery (P <0.05). The success rate at 12, 18, and 24 months after surgery was significantly lower in the group with bleb leakage than the group without.
Conclusion
The results of our study suggest that early post trabeculectomy bleb leakage negatively impacts surgical success. Furthermore, IOP reduction was lower in patients with early leakage.