ESCRS - PO005 - INVESTIGATION OF BIOMECHANICAL PROPERTIES OF LENTICULA IN FEMTOLASER CORRECTION OF MYOPIA AND MYOPIC ASTIGMATISM USING CLEAR TECHNOLOGY.

INVESTIGATION OF BIOMECHANICAL PROPERTIES OF LENTICULA IN FEMTOLASER CORRECTION OF MYOPIA AND MYOPIC ASTIGMATISM USING CLEAR TECHNOLOGY.

Published 2025 - 29th ESCRS Winter Meeting

Reference: PO005 | Type: Presented Poster & Poster | DOI: 10.82333/e93m-cz62

Authors: Tatiana Sergeevna Kuznetsova* 1 , Vladimir Antonuk 1 , Stanislav Shchukin 1 , Ivan Drozdov 1 , Alexandr Erofeev 2 , Vasiliyi Kolmogorov 2

1The Eye Microsurgery Clinic OKDC PJSC “Gazprom”, Russian Federation, Moscow,Moscow,Russian Federation, 2The National University of Science and Technology MISIS,Moscow, Russian Federation,Moscow,Russian Federation

Purpose

Femtolaser correction of myopia and myopic astigmatism is a widespread technology. As a result of the operation, the corneal lenticule is extracted. It is most often disposed of. However, the lenticule may be the key to understanding the biomechanical properties of the cornea “in vivo”, and is also a donor material. There are works in the literature on the study of lenticula: preliminary dehydration, cryopreservation, assessment of the transparency of the obtained tissue-engineered structures for creating an eye bank, study of the surface quality of the lenticula and corneal stroma after extraction of the lenticula with a low-energy femtosecond laser FEMTO LDV Z8 in an ex-vivo study (on pig eyes), assessment of diameter, central thickness, edge pachymetry, electronic scanning microscopy and histology of the lenticula.

Goal. To investigate the mechanical properties of the lenticule "in vivo".

Setting

Materials and methods: the study included 8 lenticules of 4 patients after CLEAR surgery. Patients aged from 22 to 26 years, myopia from sph(-)3.25 D to sph(-) 8.0 D, myopic astigmatism from cyl (-) 0.25 D to cyl(-) 1.25 D, IOP from 16 to 22 mmHg, pachymetry from 559 microns to 587 microns, AL from 25.76 mm to 27 mm.

 

Methods

Ion-scanning microscopy was performed on the first day after surgery after removing the lenticule from the patient's eye in order to assess the topography of the lenticula and Young's module.

Results

The measured values of the Young's modulus of the surface layers of the posterior (lower) surface of the lenticule for patients aged 22-26 years correspond to the range from 413 Pa to 580 Pa.

Conclusion

The method of scanning ion-conducting microscopy was successfully tested to obtain the topography and mapping of the mechanical properties of the lenticle in a physiological buffer

 The measured values of the Young's modulus of the surface layers of the posterior (lower) surface of the lenticula for patients aged 22-26 years correspond to the range from 413 Pa to 580 Pa.