ESCRS - FP04.01 - EVALUATING THE ACCURACY AND READABILITY OF CHATGPT-4O'S RESPONSES TO PATIENT-BASED QUESTIONS ABOUT KERATOCONUS

EVALUATING THE ACCURACY AND READABILITY OF CHATGPT-4O'S RESPONSES TO PATIENT-BASED QUESTIONS ABOUT KERATOCONUS

Published 2025 - 29th ESCRS Winter Meeting

Reference: FP04.01 | Type: Free Paper | DOI: 10.82333/n4vh-wj91

Authors: Ali Safa Balcı* 1 , Semih Cakmak 2

1Department of Ophthalmology,University of Health Sciences, Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital,Istanbul,Türkiye, 2Department of Ophthalmology,Istanbul University, Istanbul Faculty of Medicine,Istanbul,Türkiye

Purpose

This study aimed to evaluate the accuracy and readability of responses generated by ChatGPT-4o, an advanced large language model, to frequently asked patient-centered questions about keratoconus.

Setting

A cross-sectional, observational study.

Methods

This study was conducted using ChatGPT-4o to answer 30 potential questions that could be asked by patients with keratoconus. The accuracy of the responses was evaluated by two board-certified ophthalmologists and scored on a scale of 1 to 5. Readability was assessed using the Simple Measure of Gobbledygook (SMOG), Flesch-Kincaid Grade Level (FKGL), and Flesch Reading Ease (FRE) scores. Descriptive, treatment-related, and follow-up-related questions were analyzed, and statistical comparisons between these categories were performed.

Results

The mean accuracy score for the responses was 4.48 ± 0.57 on a 5-point Likert scale. The interrater reliability, with an intraclass correlation coefficient of 0.769, indicated a strong level of agreement. Readability scores revealed a SMOG score of 15.49 ± 1.74, an FKGL score of 14.95 ± 1.95, and an FRE score of 27.41 ± 9.71, indicating that a high level of education is required to comprehend the responses. There was no significant difference in accuracy among the different question categories (p=0.161), but readability varied significantly, with treatment-related questions being the easiest to understand.

Conclusion

ChatGPT-4o provides highly accurate responses to patient-centered questions about keratoconus, though the complexity of its language may limit accessibility for the general population. Further development is needed to enhance the readability of AI-generated medical content.