ESCRS - FP03.05 - TWO YEARS FOLLOW UP OF AB INTERNO CANALOPLASTY (ABIC) IN TERTIARY OPHTHALMOLOGY ACADEMIC WARD

TWO YEARS FOLLOW UP OF AB INTERNO CANALOPLASTY (ABIC) IN TERTIARY OPHTHALMOLOGY ACADEMIC WARD

Published 2025 - 29th ESCRS Winter Meeting

Reference: FP03.05 | Type: Free Paper | DOI: 10.82333/pcpf-dc10

Authors: Wojciech Wiktor Maruszczyk* 1 , Dominik Dygas 2 , Michał Bogocz 2 , Katarzyna Gontarz 2 , Marta Świerczyńska 2 , Łukasz Drzyzga 1 , Mariola Dorecka 2 , Adrian Smędowski 3 , Ewa Mrukwa-Kominek 2 , Dorota Wyględowska-Promieńska 2

1Department of Ophthalmology,Prof. K. Gibiński University Clinical Center of the Medical University of Silesia in Katowice,Katowice,Poland, 2Department of Ophthalmology,Prof. K. Gibiński University Clinical Center of the Medical University of Silesia in Katowice,Katowice,Poland;Department of Ophthalmology,Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice,Katowice,Poland, 3Department of Ophthalmology,Prof. K. Gibiński University Clinical Center of the Medical University of Silesia in Katowice,Katowice,Poland;Department of Ophthalmology,Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice,Katowice,Poland;GlaucoTech Sp. z o.o.,Katowice,Poland

Purpose

Canaloplasty is one of the minimally invasive surgical glaucoma treatment method. There are many modifications, including the ab interno and ab externo access. The procedure purpose is to improve the natural outflow of aqueous humor through the Schlemm's canal. After intervention hypotony can be avoided since aqueous is allowed to drain via the physiological outflow system. The aim of the study is to evaluate the efficacy and safety of ABiC for the treatment of open angle glaucoma in various patients in 2 years follow-up period. We have expanded the scope of the study.

Setting

Department of Ophthalmology, Prof. K. Gibinski University Clinical Centre, Medical University of Silesia in Katowice, Katowice – Poland

Methods

Patients with diagnosed glaucoma and insufficiently regulated intraocular pressure despite maximally tolerable antiglaucoma medications were selected to the study. We included 52 adult patients with various open angle glaucoma subtypes. All of them underwent ABiC procedure between 2017 to 2022 and had at least 2 years of follow-up period. Patients were treated with the modern ab-interno surgical technique using the iTrack canaloplasty microcatheter (Nova Eye Medical). Patients with 360-degree successful catheterization only were selected for this study. After the procedure we assessed the post-operative IOP, BCVA, OCT, the number of adverse events and complications and the number of antiglaucoma medications.

Results

After the procedure the mean IOP reduction and stabilisation was observed. The mean IOP was 23,31±9,10mmHg, 15,41±5,49 mmHg, 16,41±4,36 mmHg, 16,89±3,51 mmHg, 16,6±3,56 mmHg, 15,35±3,87 mmHg, 15,46±2,60 mmHg and 15,76±3,43 mmHg before, 1 day, 1, 3, 6, 12, 18, 24 months after the surgery, respectively. The mean usage of the antiglaucoma topical medications was 2,6±1,07, 1,19±1,27, 1,93±1,1, 1,74±1,1, 1,83±1,34, 1,85±1,14, 2,23±1,24 and 2,32±1,36, before, 1 day, 1, 3, 6, 12, 18 and 24 months after the surgery, respectively. There were no significant changes observed in the GCC. No decrease in BCVA and no severe complications were observed. Some of the patients after the surgery were qualified for another antiglaucoma surgery due to insufficient intraocular pressure reduction

Conclusion

Ab-interno canaloplasty appears to be a safe and effective treatment for glaucoma in all stages of the disease, although further studies are required to assess the long-term effect and late postoperative complication rate.