ESCRS - FP01.02 - TO EVALUATE RAY-TRACING FOR INTRAOCULAR LENS (IOL) CALCULATION OF A NON-DIFFRACTIVE WAVEFRONT-SHAPING EXTENDED DEPTH OF FOCUS IOL AFTER MYOPIC LASER IN-SITU KERATOMILEUSIS (LASIK) WITHOUT HISTORIC DATA.

TO EVALUATE RAY-TRACING FOR INTRAOCULAR LENS (IOL) CALCULATION OF A NON-DIFFRACTIVE WAVEFRONT-SHAPING EXTENDED DEPTH OF FOCUS IOL AFTER MYOPIC LASER IN-SITU KERATOMILEUSIS (LASIK) WITHOUT HISTORIC DATA.

Published 2025 - 29th ESCRS Winter Meeting

Reference: FP01.02 | Type: Free Paper | DOI: 10.82333/ey4t-az25

Authors: Thomas Kohnen* 1 , Titus Schug 1 , Christoph Lwowski 1 , Klemens Kaiser 1

1Ophthalmology,Goethe University Hospital,Frankfurt,Germany

Purpose

To evaluate ray-tracing for intraocular lens (IOL) calculation of a non-diffractive wavefront-shaping extended depth of focus IOL after myopic laser in-situ keratomileusis (LASIK) without historic data.

Setting

Goethe university hospital, Frankfurt

Methods

We included patients after cataract surgery with implantation of AcrySof IQ Vivity (Alcon) after myopic LASIK. Preoperative assessments included Pentacam AXL (Oculus Optikgeräte GmbH). Seven IOL calculation formulas for use in eyes after myopic LASIK have been analyzed: Potvin-Hill-Shammas-PM, Barrett True-K No History with measured (mBTK) and predicted (pBTK) posterior corneal astigmatism, OKULIX ray-tracing, PEARL DGS and PEARL DGS with posterior radial curvature (PRC), Hoffer QST, and EVO 2.0. Prediction errors (PE) were analyzed using an online tool (Eyetemis), which meets ISO standards of assessing accuracy based on precision and accuracy using robust t-tests comparing trimmed means of data with respect to heteroscedasticity.

Results

Thirty-six eyes of twenty-four patients were enrolled. Trimmed mean PE values of all formulas were not significantly different from zero, except for OKULIX ray-tracing (p<0.01). The best performing formulas in terms of trimmed mean absolute PE (tMAE) were Potvin-Hill-Shammas-PM and EVO 2.0 (both 0.30 diopters [D]). Potvin-Hill-Shammas-PM (58%) and mBTK (50%) showed the most eyes within ±0.25D. While EVO 2.0, Potvin-Hill Shammas PM and mBTK landed within ±0.50D in ≥75% of eyes, all seven formulas landed within ±1.00D in ≥89% of eyes.

Conclusion

The Potvin-Hill-Shammas-PM formula best predicted actual postoperative refraction in myopic LASIK patients in terms of tMAE and percent within target refraction.