Evaluation Of The Effect Of Pterygium And Pinguecula On Corneal Epithelial Remodelling And Stromal Configuration Using Epithelial And Stromal Mapping
Published 2022 - 40th Congress of the ESCRS
Reference: PP23.04 | Type: Free paper | DOI: 10.82333/ce0y-kx34
Authors: Idoia Goni Guarro* 1 , Iva Krolo 2 , Ines Matoc 1 , Ivanka Petric-Vickovic 1 , Valentina Lacmanovic-Loncar 1 , Ivan Sabol 3 , Zoran Vatavuk 1
1University Department of Ophthalmology,University Hospital Centre Sestre milosrdnice,Zagreb,Croatia, 2University Department of Ophthalmology,University Hospital Centre Sestre milosrdnice,Zagreb,Croatia;Optical Express Group,Zagreb,Croatia, 3Rudjer Boskovic Institute,Zagreb,Croatia
Purpose
The purpose of this study was to evaluate the results of the epithelial and stromal mapping changes affected by pterygium and pinguecula compared to results in non-affected eyes.
Setting
University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia
Methods
This cross sectional study included a total of 59 eyes divided into three groups: pterygium (PT), pinguecula (PG) and control group. Clinical assessment included: 3 consecutive measurements of stromal and epithelial mapping on Pachymetry (P) and Pachymetry Wide (PW) maps, obtained by anterior segment optical coherence tomography (AS OCT, AngioVue, AvantiRTVue-XR, Optovue, CA), and average measurement was analysed. Patients also underwent slit-lamp anterior photography and corneal tomography (Pentacam, Oculus, Germany). Exclusion criteria were ocular surface disease, other corneal pathology, previous anterior segment surgery, chronic ocular medication and contact lens use.
Results
PG showed decreased values of K2 (44.23-43.20, p=0.011) and EKR K2 (44.00-43.00, p=0.026). PG had increased central epithelial thickness (CET) (52-55, p=0.030) and increased epithelial thickness (ET) in N5 area (52-55, p=0.041). PT showed higher EKR astigmatism (0.64-1.32, p=0.013) and decreased values of K1 (43.20-41.85, p=0.025) and EKR K1 (42.97-41.89, p=0.035). PT showed decreased ET in the I (54-51, p=0.027) and SN9 areas (50-48, p=0.034) on PW. Changes of maximal (56-59, p=0.036) and minimal ET (45-42, p=0.032) were shown. PT showed higher difference between superonasal and inferotemporal ET (SN-IT) on P (20-35, p=0.015) and increased stromal thickness in N9 area (578-652, p=0.004) on PW. T-test and Mann-Whitney test were used.
Conclusions
Both PG and PT showed a significant flattening effect on corneal tomography. PG had an increased CET, while PT showed greater variability of epithelial changes and increased epithelial thickness in superonasal part of cornea, implying corneal remodelling. Increased stromal thickness in nasal areas of PT may correspond to hypoxia-induced oedema of the underlying cornea.