Relationship Between Axial Length And Corneo-Scleral Topography: A Preliminary Study

Published 2022 - 40th Congress of the ESCRS

Reference: PP12.12 | Type: ESCRS 2022 - Posters | DOI: 10.82333/fkj5-qj74

Authors: Laurent Bataille ¹ , Ainhoa Molina Martín ² , Hideki Fukumitsu ³ , David Pablo Piñero Llorens* ⁴

¹Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, ,Alicante university,alicante,Spain, ²Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, ,alicante university,alicante,Spain, ³Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, ,Alicante University,Alicante,Spain, ⁴Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy,Alicante University,Alicante,Spain

Purpose

The main objective of the current study was to investigate further the relationship of the overall length of the eye with a great variety of anterior segment parameters, including scleral geometry.

Setting

Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy,University of Alicante, Spain

Methods

64 eyes of 32 participants, with mean age 33 years, were included in this prospective non-randomized single-center study. All participants underwent a complete eye examination, including an analysis of corneo-scleral shape with a Fourier-domain profilometer. Normality of all data distributions was confirmed by means of the Kolmogorov-Smirnov test. The partial correlation test was used to assess the degree of association between the ocular axial length and the other parameters recorded, controlling for the effect of the eye (left /right). A multiple linear regression analysis was performed to define a linear model to predict the axial length from anterior segment parameters.

Results

A strong negative correlation was found between axial length and temporal-nasal ocular sagittal height difference for different chord lengths. For the right eye, a consistent and stable linear model was obtained to predict the axial length from spherical equivalent, corneal diameter, high order aberrations root mean square and minimum sagittal height for 13 and 14-mm chord. For the left eye, a model was defined to predict the axial length from spherical equivalent and mean corneal curvature, including other parameters such as corneal diameter or high order aberrations depending on the chord length considered for estimating the sagittal height values.

Conclusions

There is a correlation among anterior sagittal height measurements of the eye and its axial length. Specifically, differences between nasal and temporal sagittal heights of anterior eye correlate significantly with axial length. Likewise, the axial length can be predicted with acceptable levels of precision by means of a linear equation considering refractive, corneal and corneo-scleral variables, although the variables implied for the prediction in right and left eyes seem to differ. Further studies with a higher number of cases will be necessary to confirm the linear models defined in this study and to improve their stability and consistency.