The Effect Of Meibomian Gland Dysfunction On Laser-Assisted In-Situ Keratomileusis In Asymptomatic Patients

Published 2022 - 40th Congress of the ESCRS

Reference: PP06.17 | Type: ESCRS 2022 - Posters | DOI: 10.82333/0fv8-3d51

Authors: Oriel Spierer ¹ , Achia Nemet ² , Stav Bloch ² , Asaf Israeli ³ , Michael Mimouni* ⁴ , Igor Kaiserman ⁵

¹Ophthalmology,Wolfson Medical Center, Sackler Faculty of Medicine, Tel Aviv University,Tel Aviv,Israel, ²Sackler Faculty of Medicine, Tel Aviv University,Tel Aviv,Israel, ³Technion-Israel Institute of Technology,Haifa,Israel, ⁴Ophthalmology,Rambam Health Care Campus,Haifa,Israel, ⁵Ophthalmology,Barzilai Medical Center,Ashkelon,Israel

Purpose

To evaluate the impact of asymptomatic meibomian gland dysfunction (MGD) on laser-assisted in-situ keratomileusis (LASIK) outcomes and dry eye signs and symptoms.

Setting

An analysis of patients' charts who underwent LASIK surgery at a refractive surgical center.

Methods

Patients were divided into those who had preoperative asymptomatic significant MGD (MGD group) and those who did not have preoperative significant MGD (control group). Primary outcomes were postoperative dry eye signs and symptoms and the number of postoperative visits as a measure of adverse events.

Results

497 eyes were included in the study. Both groups had similar rates of superficial punctate keratitis (12.9% vs. 14.8%, p=0.31), postoperative complaints of dryness (32.3% vs. 34.2%, p=0.36) and postoperative number of visits (3.15 ± 0.75 vs. 3.12 ± 0.54, p=0.59). Uncorrected visual acuity (logMAR) at one month (0.026 ± 0.09 vs. 0.026 ± 0.17, p=0.99) after surgery was similar in both groups. Mean spherical equivalent was 0.03 ± 0.17 and -0.03 ± 0.18 (p=0.99) in both groups. Safety index was 1.024 ± 0.06 in the clinically significant MGD group and 1.029 ± 0.07 in the control group (p=0.45). Efficacy index was also similar in both groups (0.966 ± 0.155 and 0.979 ± 0.14, respectively, p=0.31). Myopic and hyperopic patients had similar outcomes.

Conclusions

Patients with preoperative asymptomatic MGD have similar LASIK outcomes as patients without preoperative asymptomatic MGD. Accordingly, no preoperative MGD treatment or special caution is needed in these cases.