Clinical Outcomes Of Presbyopia Correction With Presbylasik: A Systematic Review

Published 2022 - 40th Congress of the ESCRS

Reference: PO509 | Type: ESCRS 2022 - Posters | DOI: 10.82333/3qm8-4w85

Authors: Ainhoa Molina-Martín* ¹ , Joaquín Fernández ² , Carlos Rocha-de-Lossada ³ , Manuel Rodríguez-Vallejo ² , David Pablo Piñero-Llorens ⁴

¹Optics, Pharmacology and Anatomy,University of Alicante,San Vicente del Raspeig,Spain, ²Department of Ophthalmology (Qvision),VITHAS Hospital,Almería,Spain, ³Department of Ophthalmology,Hospital Virgen de las Nieves,Granada,Spain;Department of Ophthalmology (Qvision),VITHAS Hospital,Almería,Spain, ⁴Optics, Pharmacology and Anatomy,University of Alicante,San Vicente del Raspeig,Spain;Department of Ophthalmology (IMQO-Oftalmar) ,Vithas Medimar International Hospital,Alicante,Spain

Purpose

The aim of this study was to collect the scientific literature on the correction of presbyopia with laser in situ keratomileusis (presbyLASIK) in last years and to analyse the quality of such scientific evidence using validated tools.

Setting

N/A

Methods

A total of 42 articles were initially identified, but after applying the selection criteria and an additional manual search a total of 15 articles were finally included: 2 non-randomized controlled clinical trials (NRCT) and 13 case series studies. Quality assessment of NRCTs and case series was performed with the ROBINS-I and the 20-criterion quality appraisal checklist defined by Moga et al, respectively.

Results

For NRCT, the risk of bias was moderate in one study and serious in the other NRCT, being the main sources of risk, the domains related to confounding, selection of participants and measurement of outcomes. For case series studies, the main source of risk of bias was subjects not entering the study at the same point of the conditions (different levels of presbyopia). Likewise, a significant level of uncertainty was detected for a large proportion of case series for the following items: consecutive recruitment of patients, blinding of outcome assessors to the intervention that the patient received, and conclusions of the study not supported by the results.

Conclusions

Research on presbyLASIK to this date is mainly focused on case reports generating a limited level of scientific evidence. The two NRCTs identified only demonstrated the potential benefit of combining the multi-aspheric profile with some level of monovision in the non-dominant eye.