ESCRS - PO401 - Clinical Outcomes After Second-Generation Trabecular Microbypass Stents (Istent Inject®) With Phacoemulsification In Korean Patients

Clinical Outcomes After Second-Generation Trabecular Microbypass Stents (Istent Inject®) With Phacoemulsification In Korean Patients

Published 2022 - 40th Congress of the ESCRS

Reference: PO401 | Type: ESCRS 2022 - Posters | DOI: 10.82333/w5ay-kk86

Authors: Su-Ho Lim* 1

1Ophthalmology,Daegu Veterans Health service medical center,Daegu,Korea, Republic Of

Purpose

To evaluate the intraocular pressure (IOP)-lowering effect of second-generation trabecular microbypass stents (iStent® inject) with cataract extraction (combination group) and compare refractive changes in the combination group and the control (phacoemulsification only) group.

Setting

Retrospective Case-Control study

Methods

This retrospective case–control study included 36 eyes with cataract and medically controlled open-angle glaucoma with IOP < 21 mmHg and 100 non-glaucomatous eyes with cataract. Data were collected preoperatively and for 6 months postoperatively. Data included IOP, number of glaucoma medications, corrected distance visual acuity, and mean absolute error (MAE) from target refraction, and astigmatic vector analysis. Surgical success for the combination group was defined according to three criteria: (A) IOP < 15 mmHg without medication, (B) IOP < 18 mmHg without medication, and (C) IOP < 18 mmHg with or without medication.

Results

In the combination group, mean IOP was reduced from 15.1 to 12.5mmHg, and the mean number of medications decreased from 1.9 to 0.4  at postoperative 6 months (both P < 0.001). Surgical success rates were 77.8%, 83.3%, and 97.2% at 6 months by criteria A, B, and C, respectively. Mean IOP was reduced from 14.3 to 13.1mmHg at 1 month in the control group (P < 0.001). The MAE was 0.33 ± 0.26 D, and 83.3% of eyes had spherical equivalent difference within 0.50 D in the combination group (0.38 ± 0.33 D and 76.0% in the control group; P = 0.309 and P = 0.363, respectively). Preoperative and postoperative centroid values were 0.51 D @ 1°  and 0.66 D @ 178°, respectively (0.23 D @ 176° and 0.66 D @ 1° in the control group, P = 0.154 and P = 0.322). 

Conclusions

Trabecular microbypass stent (iStent® inject) with cataract extraction affords beneficial reductions in IOP and glaucoma medications and excellent refractive outcomes without severe refractive surprise in our interim experience in Korea.