The Relationship Between Serous Choroidal Detachment And Ahmad Glaucoma Valve Failure; A Coarsened Exact Matched Study

Published 2022 - 40th Congress of the ESCRS

Reference: PO383 | Type: Free paper | DOI: 10.82333/t83z-7s32

Authors: Maryam Yadgari ¹ , Nader Nassiri* ¹ , Kourosh Sheibani ²

¹Imam Hossein Medical Center,Tehran,Iran, Islamic Republic Of, ²Basir Eye Health Research Center,Tehran,Iran, Islamic Republic Of

Purpose

To investigate the effect of choroidal detachment (CD) on the success of Ahmad Glaucoma Valve (AGV) implantation.

Setting

Rassoul Akram Hospital, Tehran, Iran.

Methods

In this case-control study patients who underwent AGV implantation and developed choroidal detachment (CD) were included as the case group. A control group matched for age, sex, baseline intraocular pressure (IOP), and the number of previous glaucoma surgeries using coarsened exact matching was also included. The patients’ data including IOP, number of glaucoma medications, and complications were retrospectively extracted from the patients’ records. The primary outcome was the AGV success rate defined using two definitions; 5< IOP < 18 and a 20 percent reduction from the baseline and 5 < IOP < 15 and a 30 percent reduction from the baseline. IOP and Glaucoma medications were considered as secondary outcomes.

Results

Seventeen patients as the case group and 38 matched individuals as controls were included. The patients in the case group showed higher IOP in all time intervals. However, the average IOP reached a statistically significant difference only at month 3. (17.94 ± 6.78 vs. 13.39 ± 3.09, P= 0.003). Using the first definition, the mean duration of survival was significantly shorter in patients with CD (10.4 ± 0.7 months vs. 11.7 ± 0.2 for controls LogRANK= 4.1, P= 0.04). Among all patients, the cumulative probability of success was 98.2% and 89.1%, and 89.1% in months 3, 6 and 12 respectively, with the first definition. The corresponding value for the second definition was 81.8 %, 69.1 %, and 65.5 % in months 3, 6, and 12, respectively.

Conclusions

Choroidal detachment after AGV implantation could be a risk factor for failure after 12 months. The patients experiencing CD in the postoperative period had significantly lower survival duration. A larger, prospective study with a longer follow-up duration is suggested to further confirm the results of the present study.