Bilateral Keyser Fleischer Ring In Wilson Disease

Published 2022 - 40th Congress of the ESCRS

Reference: PO371 | Type: ESCRS 2022 - Posters | DOI: 10.82333/3k6d-np81

Authors: Amine Ennejjar ¹ , Taha Boutaj* ¹ , Salma Moutamani ¹ , Abdellah Amazouzi ¹ , Lalla Ouafa Cherkaoui ¹

¹Ophthalmology A,Hôpital des spécialités,Rabat,Morocco

Purpose

To report the case of a 36-year-old patient with a history of Wilson's disease who presented a bilateral Kayser-Fleischer ring.

Setting

Department of Ophthalmology A. Hopital des specialites. Rabat. Morocco

Methods

We report the case of a 36-year-old male patient, from a consanguineous marriage, with a history of Wilson's disease in its three clinical forms, hepatic, neurological and psychiatric.

Results

Visual Acuity was 7/10 in both eyes. Intraocular pressure was normal. Examination of eyelid found a meibomite. Bio-microscopic examination objectives a bilateral Keyser Fleischer ring. The anterior chamber was normal. After dilation, the examination of the lens is normal. The fundus was unremarkable. The biological assessment shows a low blood level of ceruloplasmin at 10 mg/dl and a high 24-hour cupruria at 126 micrograms. Brain MRI reveals generalized signal change, gliosis, and atrophy of the thalamus and brainstem.

Conclusions

Wilson disease is a rare, autosomal recessive disorder caused by abnormal copper accumulation in the body particularly involving the brain, liver, and cornea. Ophthalmologic manifestations are one of the criteria used to establish a provisional diagnosis of Wilson's disease. It can be treated and managed if it is diagnosed early.