Anterior Segment Optical Coherence Tomography Parameters In Pseudoexfoliation Syndrome

To compare anterior segment and angle parameters in pseudoexfoliation syndrome (PEX) to normal control subjects using anterior segment optical coherence tomography (AS-OCT)

departement of ophtalmology, military hospital of Tunis

we’ve conducted cross-sectional study including 22 eyes of 22 patients with PEX and 24 eyes of 24 healthy control subjects. All subjects underwent a complete ophthalmologic examination including gonioscopy and Intra Ocular Pressure. The anterior segment and angle parameters were evaluated using AS-OCT.

the two groups’ demographic characteristics were comparable. There was no statical difference in the central corneal thickness between the PEX and control group (mean corneal thickness in PEX and PEXG group: 567,01 um versus 560,06 um). The anterior chamber was significantly shallower in PEX group then control group with P<0.001. A statistically significant decrease in the anterior chamber angle parameters was found between PEX and control group. In all the patients of the PEX group, the PEX deposits were correctly visualised by OCT of anterior segment after their identification by biomicroscopy.

the anterior chamber angle tends to be narrower in PEX patients which may suggest its potential role in the progression of PEX to PEX glaucoma. Its early detection may be the key to a more proper management of PEX glaucoma.