ESCRS - PO032 - Descemet Membrane Endothelial Keratoplasty Patching (Dmep) – Selective Endothelial Replacement In Eyes With Localised Endothelial Dysfunction After Six Months.

Descemet Membrane Endothelial Keratoplasty Patching (Dmep) – Selective Endothelial Replacement In Eyes With Localised Endothelial Dysfunction After Six Months.

Published 2022 - 40th Congress of the ESCRS

Reference: PO032 | Type: Case report | DOI: 10.82333/zg11-fj43

Authors: Luis García-Onrubia* 1 , Nick Stanojcic 1 , Maninder Bhogal 1

1Corneal department,St Guy´s and Thomas´ Trust Foundation,London,United Kingdom

To show the clinical outcomes of a series of cases in which a Descemet's membrane endothelial keratoplasty patching (DMEKP) was adjusted to the dysfunctional endothelial cell area.

St Guy´s and Thomas´ Trust Foundation, Department of Ophthalmology, London, United Kingdom

Eight patients were included in this cases series. Indications for DMEP were Fuchs heterochromic iridocyclitis (n=1), Fuchs’ endothelial dystrophy (n=4), endotheliitis (n=3). In all cases, a custom-made DMEP graft was used, being the size of the graft less than our standard 8-mm DMEK graft size. In all cases, complete graft attachment was achieved, and the corneas were cleared, reducing the steroids in the short post-operatory period without any graft rejection reported in 6 months´ time.

Endothelial grafts matching the area of dysfunction were produced to preserve healthy host cells and limit the immunological burden of new grafts.