Trans-Prk For Correction Of Myopic Astigmatism: Customised Versus Aberration-Free Treatment

To compare the results of trans-epithelial photorefractive keratectomy (trans-PRK) with corneal wave-front guided customized ablation compared to aberration-Free aspheric ablation for correction of combined myopic astigmatism.

 

 

New Mowasat Hospital, Kuwait.

A prospective interventional cohort study with matched retrospective control group. Fifty myopic patients with -1.00 dioptre or more astigmatism received corneal wave-front guided trans-PRK (group 1). A matching group of 50 patients treated with aberration-Free aspheric trans-PRK as control group (group 2).  All treatments were performed by the same surgeon using SCHWIND AMARIS 750S Total-Tech Laser. Mitomycin C was used in all cases. The follow-up period was 12 months. Refractive predictability, safety, and efficacy of the two methods were compared.

 

 

 

Mean preoperative spherical equivalent refraction was -4.9 D in group 1 and -5.2 D in group 2. Mean postoperative spherical equivalent at 12 months postoperatively was -0.1 (SD: 0.34) in group 1 and -0.2 (SD: 0.59) in group 2, with 92%, and 88% within 0.5 D of target refraction, respectively. Refractive outcomes at 12 months did not vary among groups (P>0.05). Mean log MAR (logarithm of the minimum angle of resolution) uncorrected distance visual acuity at 12 months was 0.00 (SD: 0.05) in group 1 and 0.05 (SD: 0.09) in group 2, with significantly better vision in group 1.

 

 

Trans-PRK with corneal wave-front guided ablation demonstrated comparable refractive outcomes to aberration-free aspheric ablation for correction of myopic astigmatism.

 Aspherical treatments have the advantage of saving tissue, time and due to their simplicity they offer a better predictability.