Normal Values Of Corneal Epithelial Thickness In A Healthy Hispanic Population With Spectral Domain Optical Coherence Tomography (Sd-Oct)

Estimate the normal epithelium corneal thickness (ECT) values in a healthy Hispanic population with the coherent optical tomograph of spectral domain

Humidity and temperature conditions from Imaging room were controlled in order to avoid variability of images. These were taken at the same time

Prospective study were included >18 yo,both sex,no ophthalmologic disease,myopic or hypermetropic < 5D,astigmatic <2D,OSDI <12,BAD-D < 1.6 and NICE < 8.Exclusion criteria were corneal surgery,use of contact lenses and non-signers informed consent.All patients were imaged, using the Cirrus HD-OCT 5000. Sample calculation was performed based on criterion of a proportion and confidence interval,assuming presence of normal epithelial thicknesses of 50%,precision estimation of 1% and a confidence level of 95% expecting a power of the study of 80%.Statistically significant difference p<0.05 CI95%

195 eyes were included. 63% female.Mean age 43 years.68.7% NICE index of 4.Mean global BAD-D 0,94.Global median ECT according to optical zones were: 48+5 um (0-2), 46+5 um (2-5), 45+4 um (5-7) and 44+4 um (7-9). There was a statistical significant difference between four global optical zones thicknesses (p<0.001). Comparing our results with data published by Sadda et al, there was only a statistical significant difference in 7-9 mm optical zone epithelial thickness global evaluation (p=0.001).Statistically significant difference between gender in 0-2mm,2-5mm,5-7mm OZ being thicker in males

We have reported ECT in healthy Hispanic subjects. We didn´t find a difference with the previous publications in other populations being able to access treatment tested in those populations and adapt them to ours