Distribution Of Ocular Higher Order Aberrations Of The 3Rd And 4Th Order For Two Age Groups

Published 2022 - 40th Congress of the ESCRS

Reference: FPS03.07 | Type: Free paper | DOI: 10.82333/9b1n-db78

Authors: Nikola Henningsen* ¹ , Louise Blöck ¹ , Sarah Rosenzweig ¹ , Giacomo Savini ² , Joaquín Fernández ³ , Gerd Auffarth ¹

¹Dept. of Ophthalmology,University Hospital Heidelberg,Heidelberg,Germany, ²G.B. Bietti Foundation IRCCS,G.B. Bietti Foundation IRCCS,Rome,Italy, ³QVision,Vithas Hospital Almería ,Almería,Spain

Purpose

To investigate the distribution of ocular higher order aberrations in healthy eyes for a younger and an elderly population.

Setting

Department of Ophthalmology at the Heidelberg University Hospital, Germany.

I.R.C.C.S.-G.B. Bietti Foundation, Rome, Italy.

QVision / Vithas Hospital Almeria, Almeria, Spain.

Methods

In this ongoing study, phakic eyes without any known ocular pathologies were measured with the Pentacam AXL Wave. These Measurements (only measurements with good quality scores were included) were retrospectively analysed according to the ocular higher order aberrations (HOA). The data was clustered with respect to the age of the patients into two groups – a younger (≤ 50 years) and an elderly (> 50 years) group. The HOA of the 3^rd and 4^th order (Trefoil, Coma, Spherical Aberrations, Quadrafoil and sec. Astigmatism) were analysed always for the optical zones of 2, 3 and 4mm.

Mean values and standard deviations were calculated for both study groups, means were compared with an independent t-test.

Results

252 eyes were included in this study. The patients in the younger group (191 eyes) were 32±9,4 y old. The patients in the elderly group (162 eyes) were 65±10,2 y old.

Trefoil_2mm: mean=0,018_Y/0,043_Eµm*; Trefoil_3mm: mean=0,037_Y/0,072_Eµm*; Trefoil_4mm: mean=0,059_Y/0,108_Eµm*; Coma_2mm: mean=0,033_Y/0,043_Eµm*; Coma_3mm: mean=0,032_Y/0,059_Eµm*; Coma_4mm: mean=0,059_Y/0,099_Eµm*; Quadrafoil_2mm: mean=0,011_Y/0,022_Eµm*; Quadrafoil_3mm: mean=0,017_Y/0,033_Eµm*; Quadrafoil_4mm: mean=0,024_Y/0,046_Eµm*; sec.Astigmatism_2mm: mean=0,007_Y/0,017_Eµm*; sec.Astigmatism_3mm: mean=0,015_Y/0,028_Eµm*; sec.Astigmatism_4mm: mean=0,024_Y/0,039_Eµm*; SA_2mm: mean=0,004_Y/0,005_Eµm; SA_3mm: mean=0,012_Y/0,025_Eµm*; SA_4mm: mean=0,028_Y/0,057_Eµm*. An * indicates a sig. diff. (p<.05) between means.

Conclusions

It could be confirmed that elderly eyes have statistically significant greater ocular higher order aberrations than younger. This finding was consistent for all higher order aberrations of the 3^rd and 4^th order regardless of the size of the optical zones analysed, except one case.

This ongoing study provides an excellent basis in order to establish normative data for HOA. However, a much greater population, including patients of all age groups, must be examined so that a more meaningful clustering, e.g. 10 years steps, can be applied.