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Influence of ocular biomechanics ocular rigidity and loss of accommodation on age-related changes in the eye organ: a new potential clinical significance

Session Details

Session Title: Special Issues

Session Date/Time: Friday 15/02/2013 | 08:30-10:00

Paper Time: 09:41

Venue: Hall 2

First Author: : A.Hipsley USA

Co Author(s): :    G. Waring IV   J. Wang   E. Hsiao        

Abstract Details


To present an ocular biomechanical model to demonstrate the effects of ocular rigidity and the loss of accommodation as a potential correlation with ocular pathogenesis. To discuss the potential new clinical significance of understanding the impact of ocular Biomechanical dysfunction as it relates to ophthalmology treatment paradigms.


This study was performed at National Taiwan University in Department of Biomedical Engineering.


Accommodation physiology and function have been much discussed in the literature, while the impact that ocular biomechanics has on the overall function of the eye organ has been significantly neglected. Ocular Rigidity and biomechanical dysfunction of accommodation as it relates to age-related pathogenesis are presented with relation to clinical significance. Evidence Based analysis of the pathophysiology of aging of the ocular organ both macroscopic & microscopic is presented.


The pathophysiology of the aging oculus has tremendous impact on ocular biomechanics and its influence not only on visual function (loss of accommodation), but also on the propensity for age-related ocular diseases. Ocular rigidity, in particular, has been evidenced to show correlations with age, loss of accommodation function, IOP, POBF, bio transport and hydrodynamic functions of the eye organ. The understanding of these complex biomechanical interactions have potential new clinical significance.


Understanding the impact of ocular biomechanics, ocular rigidity and loss of accommodation as it relates to the detection and treatment of age-related conditions of the eye including presbyopia, glaucoma, macular degeneration and cataract formation could produce a potential for developing new ophthalmic treatment paradigms. Addressing ocular biomechanics may also aid in new developments for restorative procedures and preventative approaches which may have an ongoing health component to the ocular organ.

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