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New surgical approach in the management of keratoconus, intralamellar strengthening keratoplasty (ISK)

Poster Details

First Author: R.Bagh RUSSIA

Co Author(s):    V. Mamikonyan   G. Osipyan   H. Khraisten              

Abstract Details


To evaluate the efficacy of the new technique (intralamellar strengthening keratoplasty ISK) in the management of keratoconus.


Research Institute Of Eye Diseases, Moscow, Russia.


In 120 eyes of 110 patients with progressive keratoconus, after formation of ring-shaped intra corneal pocket using Femtosecond laser technique, segment of a modified ring-shaped stromal transplant collected from donor’s eye, also created by femtosecond laser is inserted in the corneal pocket. Uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), slit lamp examination, corneal topography and anterior segment optical coherence tomography (OCT) were evaluated before and up to 48 months after surgery.


Mean patient age was 33 ± 13 years-old. Corneal thinnest point was 410 ± 70 µm. Mean preoperative UCVA and BSCVA were 0.09 ± 0.06 and 0.43 ± 0.14, respectively. Mean UCVA and BSCVA at 3 months postoperative improved to 0.52 ± 0.12 and 0.61 ± 0.12, respectively. Mean preoperative K max in optical zone was 49.7 ± 5.3, improved to 45.8 ± 5.2 postoperative. One patient presented intrastromal haze of unknown etiology that improved during the follow-up. In all eyes, no signs of a progressing keratoconus were found. Corneal thickness and refractive values remained stable within the observation period.


The new technique, intralamellar strengthening keratoplasty (ISK) for management of keratoconus is safe and effective. ISK resulted in stabilization of KC, significant increase in UCVA and BSCVA, improvement in central corneal topography and decrease in myopia and astigmatism.

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