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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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Topography-modified refraction (TMR): partial to total adjustment of treated cylinder amount and axis provided by topography data measured vs using the standard clinical refraction in myopic topography-guided LASIK

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Session Details

Session Title: Presented Poster Session: Refractive Surgery New Techniques/Instrumentation/Devices I

Venue: Poster Village: Pod 2

First Author: : A.Kanellopoulos GREECE

Co Author(s): :                           

Abstract Details


The purpose of this study is to compare the outcomes of 50% and 100% Topography-Modified Refraction (TMR) to each other and to the standard clinical refraction in patients having myopic topography-guided LASIK for myopia.

Setting: Clinical and Research Eye Institute, Athens, Greece


In this contralateral, prospective randomized consecutive case series, 296 eyes (148 patients) have undergone myopic (with corresponding astigmatism) topography-guided LASIK. One eye of each patient (Group-A) was treated with the standard clinical refraction (sphere, cylinder and axis), while the contralateral eye with: either 50% Topography-modified refraction (TMR) (group-B); or 100% Topography-modified refraction (TMR) (group-C); The 3 months peri-operative visual performance and refractive data were compared for all three groups.


Mean pre-operative refractive error was: −5.5 D of myopia and −1.75 D of astigmatism. In average numbers at 3 months: UDVA: group A was 20/20, group B 20/18 and 20/16 for group C; CDVA: 20/20, 20/16.75 and 20/13.5 respectively; 1 line of vision gained: 27.8%, 41.7% and 55.6%; 2 lines of vision gained was 5.6%, 8.7% and 11.1% also respectively. In-group A, 27.8% of eyes had over −0.50 diopters of residual refractive astigmatism, 17.7% in group B (P<.01) and to 11.7% in group C(P<.01). All values were statistically different when group B was compared to group C.


Topography-modified refraction (TMR) used in myopic topography-guided cases, appears superior to clinical refraction used. Complete adherence to the topography cylinder amount and axis appears to offer the best outcomes in this contralateral eye comparison.

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