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A review of ICE syndrome features: should we always follow the classic definition?

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Session Details

Session Title: Presented Poster Session: Glaucoma

Venue: Poster Village: Pod 2

First Author: : S.Mahmah ALGERIA

Co Author(s): :    N. Haouari   M. Terahi                    

Abstract Details


The purpose of this presentation is to expose the classic characteristics of the iridocorneal endothelial syndrome, the management challenges and to describe an atypical case of CHANDLER syndrome with bilateral form.


Nafissa Hamoud Hospital - Algeria


We present a 46-year-old patient with Chandler's syndrome. Our patient shared many of the classic characteristics of Chandler's syndrome, including peripheral anterior synechiae and corneal edema, with unusual bilateral aspect--the patient was male.We illustrate the clinical aspect,specular microscopy and OCT images of the case, Details regarding the subsets of the ICE syndrome, differential diagnosis, and current understanding of the pathophysiology are also reviewed


Chandler syndrome is the most common of the clinical variants and makes up approximately 50% of the cases of ICE syndrome, The condition is clinically unilateral, presents between 2 0 and 5 0 years of age, and occurs more often in women. Our patient was male and although cases of bilateral involvement have been described, that make us thoughts that the diagnosis of ICE syndrome must always be considered in young to middleaged patients who present with uni ou bilateral secondary ACG


The ICE syndrome is a progressive anterior segment disease that is quite difficult to manage. Corneal edema, increased IOP, and glaucoma are all sequelae of these conditions and, even in the best hands, are extremely challenging to manage. Today, nearly 100 years after Harms described the first patient with an ICE syndrome, we still do not know the exact mechanism for the corneal endothelial changes. Hypertonic saline solutions and medications to reduce the lOP, when elevated, can be effective in controlling the corneal edema. Further investigation is needed to determine the most-appropriate treatment and management of the ICE syndrome

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