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Efficacy of corneal cooling on postoperative pain management after photorefractive keratectomy: a contralateral eye randomised clinical trial

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Session Details

Session Title: Surface Photoablation/PRK

Session Date/Time: Tuesday 25/09/2018 | 14:00-16:00

Paper Time: 14:24

Venue: Room A3, Podium 2

First Author: : M.Abrishami IRAN

Co Author(s): :    S. Zarei-Ghanavati   N. Nosrat                 

Abstract Details


To compare chilled and room temperature balanced salt solution (BSS) and bandage contact lens (BCL) on post photorefractive keratectomy (PRK) pain.


Eye Research Center, Khatam Eye Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.


In a prospective, single-masked, controlled eye study, one hundred eyes of fifty patients were divided into two groups which received room temperature or chilled BSS and BCL in each eye, and compared for post-PRK pain. Three different pain evaluation systems were used to evaluate pain between the groups at 1 and 6 h and days 1, 2, 3, 5, and 7, postoperatively.


The mean spherical equivalent of preoperative refractive error in both groups was not statistically significantly different (-4.18±1.5 in chilled and -4.19±1.7 in room-temperature groups, P=0.94). The mean time of epithelial healing was 6.16 ± 1.7days in the chilled and 6.10 ± 1.59 in the room temperature group (P=0.32). Best corrected visual acuity (BCVA) at 1 month was 0.013 ± 0.03 in the chilled group and 0.014 ± 0.04 in the room temperature group postoperatively (in logMAR scale) (P 0.84). No statistically significant difference was found between the two groups by any of the three pain scoring systems.


Chilled BSS and BCL do not seem to be superior to room temperature in reducing post-PRK pain.

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