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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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Pentacam top indices for diagnosing subclinical and definite keratoconus

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Session Details

Session Title: Anterior Segment Imaging II

Session Date/Time: Tuesday 25/09/2018 | 08:00-10:30

Paper Time: 09:22

Venue: Room A4

First Author: : S.Goel INDIA

Co Author(s): :                        

Abstract Details


To determine pachymetric and topometric indices in patients with definite and subclinical keratoconus and the validity of these indices in the diagnosis of keratoconus.


anand hospital and eye centre, jaipur, india


We evaluated 100 keratoconic and 97 healthy eyes in this study. Pentacam(OCULUS) examination was performed for all participants, and the data of all pachymetric and topometric indices was extracted for the study population.


The average of all evaluated pachymetric and topometric indices showed a significant difference between the study groups (p < 0.001). Belin/Ambrosio Deviation Display (BAD_D), Index of Vertical Asymmetry (IVA), Index of Surface Variance (ISV) were identified as the best diagnostic criteria for the diagnosis of subclinical keratoconus and BAD_D, mean keratometry and 3rd order vertical coma aberration were identified as the best diagnostic criteria for the diagnosis of definite keratoconus (R2 = 0.91, p <0.001). The sensitivity and specificity of the above-mentioned models were 83.6% and 96.9%, and 97.9% and 96.9%, respectively.


Simultaneous evaluation of BAD_D, 5th order vertical coma aberration, IVA, and ISV, especially when the pattern of the corneal curvature is normal, can detect subclinical keratoconus with high sensitivity and specificity. As for definite keratoconus, each of the BAD_D, mean keratometry, and 3rd order vertical coma aberration indices has a desirable diagnostic validity. However, the aforementioned indices do not negate the importance of widely recognized and acceptable indices like keratometry and central corneal thickness.

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