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Corneal transplantation in Universiti Kebangsaan Malaysia Medical Centre (UKMMC): a clinical audit

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Session Details

Session Title: Orbis Treatment and Prevention of Blindness in the Developing World

Session Date/Time: Monday 24/09/2018 | 12:15-12:45

Paper Time: 12:39

Venue: Stolz 1

First Author: : A.Zahidin MALAYSIA

Co Author(s): :    A. J   A. M   T. CS   A. M   A. MA   W. Wan Abdul Halim     

Abstract Details


Corneal transplantation had been done in UKMMC since 2008. This research was intended to document the surgical outcome and the incidence of complication of corneal transplantation surgery at 3, 6 and 12 months post-operatively in UKMMC.


Ophthalmology Department, Universiti Kebangsaan Malaysia Medical Centre.


This is a retrospective cohort study.Data were collected from the Cornea transplant registry at UKMMC and patients’ medical records. Patients selected had underwent corneal transplant surgeries from 2008 until 2013. Pre-operative comorbid conditions, post-operative visual acuity (VA), graft survival and complications were analysed at 3, 6 and 12 months.A total of 111 post-keratoplasty eyes [72 post-Penetrating Keratoplasty (PK), 26 post-Descemet’s Stripping Endothelial Keratoplasty (DSEK) and 13 post-Deep Anterior Lamellar Keratoplasty (DALK) eyes] were analysed.


The most common ocular comorbidity was glaucoma (22.5% n=25). Graft survival at 12 months was highest for post-DALK eyes (92.3%, n=12) followed by post-PK (75.0%, n=54) and post-DSEK eyes (57.7%, n=15). Post-PK and post-DSEK eyes showed statistically significant improved visual outcome after 12 months. Post-operative 1-year VA was best recorded in post-DALK eyes (logMAR=0.39) followed by post-PK (logMAR=1.00) and post-DSEK eyes (logMAR=1.15), p<0.05. The highest rate of complication encountered after the surgery was ocular hypertension (24.3%, n=41), suture-related problem or suture abscess (21.9%, n=37), cornea vascularization (20.7%, n=35) and graft failure (13.6%, n=23).


Post-DALK eyes had the highest graft survival at 1 year. Most eyes showed excellent 1-year visual outcome following corneal transplantation surgeries in UKMMC. Ocular hypertension was the most common post-operative complication.

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