Official ESCRS | European Society of Cataract & Refractive Surgeons


Optic nerve perfusion analysis with glaucoma angio-OCT

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Session Details

Session Title: Presented Poster Session: Glaucoma II

Venue: Poster Village: Pod 3

First Author: : S.García-Delpech SPAIN

Co Author(s): :    A. Hervás   P. Udaondo   E. Sanz Marco                 

Abstract Details


Optical Coherence Tomography-Angiography (OCT-A) detect changes in the perfusion of the optic disc in patients with glaucoma disease.


The study was done at AIKEN clinic, Valencia, Spain.


We studied 35 eyes of 20 patients using high-speed OCT (AngioVue, Imex). The amplitude-angular deviation algorithm (SSADA) of the divided spectrum is used to calculate the angiography of the three-dimensional optical disk. A disk flow index was calculated from 4 recorded scans. Widefield OCT scanning on nightclubs can measure the thickness of the retinal nerve fiber (NFL) layer. The variability is evaluated by the coefficient of variation (CV).


In normal eyes, a dense red microvascular is visible in angio-OCT. This network was attenuated in subjects with glaucoma. The disc flow rate was reduced by 25% in the glaucoma group (P = 0.003). (15% mild, 10% moderate, 5% severe). The sensitivity and specificity were 100% using an optimized cut. The flow index was highly correlated with the standard deviation of the visual field pattern.


With the Angio-OCT, repeated measurements of the optic disc perfusion can be useful in the evaluation of glaucoma and its progression. More clinical investigations are necessary to confirm these promising results.

Financial Disclosure:


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