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Posterior capsule opacification with two hydrophobic acrylic intraocular lenses: Vivinex XY1 vs Acrysof SN60WF - 3 year results of a randomised trial

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First Author: C.Leydolt AUSTRIA

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Abstract Details


To compare the incidence and intensity of posterior capsule opacification (PCO) and Nd:YAG capsulotomy rates between two similar open-loop single-piece hydrophobic acrylic intraocular lenses (IOLs) but differences in the proprietary material characteristics and the design features over a period of 3 years.


Department of Ophthalmology, Medical University Vienna


The randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison comprised 80 patients (160 eyes) with bilateral senile cataract. All patients had bilateral cataract surgery in both eyes and received a Vivinex XY1 IOL in one eye and an Acrysof SN60WF IOL in the other eye. Follow-up examinations were performed three years after surgery. Digital retroillumination images were taken of each eye. The amount of posterior capsule opacification (score: 0 – 10) was assessed subjectively at the slit-lamp and objectively using automated image analysis software (AQUA).


The objective PCO score of the Vininex XY1 IOLs was 0.9 ± 0.8 compared to the PCO score of 1.4 ± 1.1 for the Acrysof SN60WF IOLs (p < 0.001). 11.4 % of patients had a neodymium:yttrium-aluminium-garnet (Nd:YAG) capsulotomy in the Vininex XY1 eye, and 18.6% had a capsulotomy in the Acrysof SN60WF eye (p = 0.001) three years postoperatively.


The new hydrophobic acrylic Vininex XY1 IOL showed significantly lower PCO and YAG rates compared to the Acrysof SN60WF IOL. The interaction of various factors such as hydrophobic material, smooth optic surface and sharp posterior optic edge is the major key for PCO prevention.

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