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Evaluation of endothelial cell density and loss following I track ab-interno canal based surgery

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First Author: D.Lubeck USA

Co Author(s):    R. Noecker                    

Abstract Details


To evaluate endothelial cell density, loss and stability over a three-year period in patients who have undergone ab-interno canal based glaucoma surgery using the iTrack surgical system (Ellex, Adelaide, Australia) combined with cataract surgery.


Prospective, multi-center registry study with patients followed for 36 months following iTrack ab-interno canal based glaucoma surgery combined with cataract surgery.


Specular microscopy was performed preoperatively and at 1, 6, 12, 24, and 36 months postoperatively. Standard metrics for glaucoma surgery follow-up were also measured including visual acuity, intraocular pressure, visual fields, optic nerve OCT and glaucoma medication use. Endothelial cell density and loss were analyzed at each time point. Results from patients undergoing iTrack combined with cataract surgery were compared with results from control groups who underwent cataract surgery alone.


Mean endothelial cell loss 1 year following iTrack ab-interno surgery combined with cataract surgery was 5%. Endothelial cell loss in the control groups of FDA pivotal MIGS trials undergoing cataract surgery alone was 10% and 12.3%.


iTrack ab-interno canal based glaucoma surgery causes minimal endothelial cell loss, comparable to cataract surgery alone. Future analyses will assess longer term endothelial cell stability.

Financial Disclosure:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, ... receives consulting fees, retainer, or contract payments from a competing company

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