Result of the 2-staged treatment of keratoconus with implantation of the intracorneal segments and corneal collagen crosslinking.

Session Details

Session Title: Cornea

First Author: Farah Abdulaliyeva Azerbaijan

Co. Authors :    Inara Abbasova    Mirana Mirishova                  

Abstract Details:



To value the results of the II-III stage keratoconus treatment (by Amsler) by the introstromal keratoplasty method with implantation of segments with corneal collagen crosslinking.


National Ophthalmology Center named after acad. Z.Aliyeva, Azerbaijan.


15 patients (18 eyes) with keratoconus of II and III stages by Amsler (7 and 11 eyes accordingly) were included to the investigation all patients were subjected to the intrastromal keratoplasty with implantation of one or two intracorneal segments Keraring (""Mediphacos""). Implantation was made into the depth, equal to the 2/3 of corneal thickness. During 3-5 days after segments implantation we'd performed the crosslinking of cornea on the CBM Vega (""BON"") apparatus using riboflavin- Ricrolin (""BON""). Total time of ultraviolet irradiation exposure with the wave length of 370nm has made up 30 minutes. Preoperative examination had revealed the mean values of next data: UCVA was 0.05±0.2; BSCVA was 0.2±2.2; refraction spheroequivalent -8.1±2.4D; cylindrical component 8.5±2.9D; keratometry 55.5±1.8D; refraction value in the ectasia zone 59.4±1.2D; thickness of cornea on the center 406±2.6µ.


In all patients we're observed the successive decrease of the refractive induces after the performed surgeries. In 6-12 months postoperatively the spheroequivalent in average was -2.2±1.6D; cylindrical component in average was -1.8±1.1D. According to the topography data of cornea the considerable decrease of refraction strength in the ectasia zone till 46.5±1.5D and also the deviation of zone of the largest ectasia towards the center. According to the OCT data the corneal thickness varied in the postoperative period: during the first two months after the intervention the decrease of the corneal thickness in the average was by 25±1.2µ ; in 6 months the in induces of pachymetry were stabilized and were 385±1.2µ in average. Postoperatively the visual improvement in all patients was noted. Visual acuity without correction was 0.5±0.2; with the maximal spectacles correction 0.8±0.7. More than 95% of the eyes had a post-operative UCVA which was better than or equal to the preoperative BSCVA.


The combination of two treatment methods - implantation of the intracorneal segments and corneal collagen crosslinking - makes it feasible to get the high functional results and stabilization of the progressing disease.

Financial Disclosure: