Amsterdam 2013 Programme Satellite Meetings Registration Exhibition Virtual Exhibition Hotels Visa Letter Invitation
Search Abstracts by author or title
(results will display both Free Papers & Poster)
Back to Freepaper Session

Comparison of corneal sensation between small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis for myopia

Session Details

Session Title: Refractive Femtosecond

Session Date/Time: Sunday 06/10/2013 | 17:00-18:30

Paper Time: 18:00

Venue: Elicium 2 (First Floor)

First Author: : M.Li CHINA

Co Author(s): :    X. Zhou   J. Zhao   Y. Shen   Y. Yu   F. Lee   L. Gong

Abstract Details


To compare the impact on corneal sensation after Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser Assisted Laser In Situ Keratomileusis (Femto-LASIK) in myopic patients.


Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.


In this prospective nonrandomized comparative study, 71 patients were enrolled into this study. Thirty-eight eyes of 38 patients underwent SMILE surgeries, and 33 eyes of 33 patients underwent Femto-LASIK surgeries. Corneal sensation was tested with Cochet-Bonnet esthesiometry in five areas (central, superior, inferior, temporal, and nasal quadrants) within caps or flaps preoperatively, and at 1 week, 1, 3, and 6 months postoperatively. Comparison of corneal sensation was performed between the SMILE group and Femto-LASIK group. Additionally, the correlations were evaluated between the postoperative central corneal sensitivity and preoperative spherical equivalent (SE), and ablation depth at all postoperative visits.


All areas within the cap or flap demonstrated corneal hypoesthesia immediately after both surgeries. SMILE-treated eyes showed less compromised corneal sensation than Femto-LASIK-treated eyes at all postoperative visits in the central (all P < 0.05), inferior (all P < 0.05), nasal (all P < 0.05), and in the lateral area at the 1-week (P < 0.05) and 1-month (P < 0.05) visits. In the SMILE group, the inferior, nasal, and temporal quadrants recovered faster than other areas. In the Femto-LASIK group, the sensation over the entire flap did not recover to preoperative levels by postoperative 6 months. There was no correlation between postoperative central corneal sensation and preoperative SE, and ablation depth at all postoperative follow-up visits in both groups (all P > 0.05).


The impairment of corneal sensation is less severe in SMILE-treated eyes than in Femto-LASIK-treated eyes. Recovery of corneal sensation is faster after SMILE than after Femto-LASIK. The loss of central corneal sensation is independent of preoperative SE or ablation depth.

Financial Interest:


loading Please wait while information is loading.